Syphilis in Nepal:
Symptoms, Stages & Cure
A complete medical guide to understanding "Bhayankar Rog" (Syphilis) from early detection to advanced treatment protocols in Kathmandu.
Medically Reviewed
What is Syphilis?
Syphilis is a complex bacterial infection caused by Treponema pallidum. Historically feared in Nepal as 'Bhayankar Rog' due to its destructive nature, it is now easily diagnosable and 100% curable with modern antibiotics. It primarily spreads through direct contact with a syphilis sore (chancre) during sexual activity. If left untreated, it progresses through four distinct stages, potentially causing permanent damage to the brain, heart, and nervous system.
[рдиреЗрдкрд╛рд▓реА] рд╕рд┐рдлрд┐рд▓рд┐рд╕ 'рдЯреНрд░реЗрдкреЛрдиреЗрдорд╛ рдкреНрдпрд╛рд▓рд┐рдбрдо' рдЬреАрд╡рд╛рдгреБрдмрд╛рдЯ рд╣реБрдиреЗ рдПрдХ рдЬрдЯрд┐рд▓ рд╕рдВрдХреНрд░рдордг рд╣реЛред рдиреЗрдкрд╛рд▓рдорд╛ рдпрд╕рд▓рд╛рдИ рдРрддрд┐рд╣рд╛рд╕рд┐рдХ рд░реВрдкрдорд╛ 'рднрдпрдВрдХрд░ рд░реЛрдЧ' рднрдирд┐рдиреНрдереНрдпреЛред рдЕрд╣рд┐рд▓реЗ рдЖрдзреБрдирд┐рдХ рдПрдиреНрдЯреАрдмрд╛рдпреЛрдЯрд┐рдХрдмрд╛рдЯ рдпрд╕рдХреЛ рдкреВрд░реНрдг рдЙрдкрдЪрд╛рд░ рд╕рдореНрднрд╡ рдЫред рдпреЛ рдЕрд╕реБрд░рдХреНрд╖рд┐рдд рдпреМрди рд╕рдореНрдкрд░реНрдХрдмрд╛рдЯ рд╕рд░реНрдЫ рд░ рдЙрдкрдЪрд╛рд░ рдирдЧрд░реЗрдорд╛ рдпрд╕рд▓реЗ рд╢рд░реАрд░рдХрд╛ рдореБрдЦреНрдп рдЕрдВрдЧрд╣рд░реВрдорд╛ рд╕реНрдерд╛рдпреА рдХреНрд╖рддрд┐ рдкреБрд░реНтАНрдпрд╛рдЙрди рд╕рдХреНрдЫред
The Nepal Context
In our Kathmandu clinic, we've observed specific trends regarding Syphilis in the Nepali population:
- Hidden Prevalence: Many cases go undiagnosed in the 'Latent' stage where no symptoms are visible.
- Congenital Concerns: Testing during pregnancy is vital to prevent transmission to newborns, a significant public health focus in Nepal.
- Migrant Health: We frequently screen individuals returning from abroad where exposure risks may have been higher.
- VDRL Accuracy: While VDRL is the standard screening in Nepal, we emphasize confirmatory TPHA testing for all reactive results.
Stage 1: Primary Syphilis
The hallmark of the primary stage is the 'Chancre'тАФa small, firm, and painless sore. It typically appears 3 weeks after infection at the site of entry (genitals, anus, or mouth). Because it is painless and often hidden, many patients in Nepal miss this crucial warning sign.
[рдиреЗрдкрд╛рд▓реА] рдкрд╣рд┐рд▓реЛ рдЪрд░рдгрдорд╛ 'Chancre' рднрдирд┐рдиреЗ рд╕рд╛рдиреЛ, рдХрдбрд╛ рд░ рдирджреБрдЦреНрдиреЗ рдШрд╛рдЙ рджреЗрдЦрд┐рдиреНрдЫред рдпреЛ рд╕рдВрдХреНрд░рдордг рднрдПрдХреЛ рдХрд░рд┐рдм рей рд╣рдкреНрддрд╛рдорд╛ рджреЗрдЦрд╛ рдкрд░реНрдЫред рдирджреБрдЦреНрдиреЗ рд╣реБрдирд╛рд▓реЗ рдзреЗрд░реИрд▓реЗ рдпрд╕рд▓рд╛рдИ рд╡рд╛рд╕реНрддрд╛ рдЧрд░реНрджреИрдирдиреН, рдЬреБрди рдкрдЫрд┐ рдЧрдПрд░ рдЦрддрд░рдирд╛рдХ рд╣реБрди рд╕рдХреНрдЫред
Critical Note
The sore will heal on its own even without treatment. This does NOT mean you are cured; the bacteria is simply moving deeper into your body.
Stage 2: Secondary Syphilis
Weeks after the chancre heals, a non-itchy rash may appear on the palms of your hands and soles of your feet. This is often accompanied by flu-like symptoms, swollen glands, and 'moth-eaten' hair loss. In Nepal, these rashes are sometimes mistaken for common skin allergies.
[рдиреЗрдкрд╛рд▓реА] рдШрд╛рдЙ рдирд┐рдХреЛ рднрдПрдХреЛ рдХреЗрд╣реА рд╣рдкреНрддрд╛рдкрдЫрд┐ рд╣рддреНрдХреЗрд▓рд╛ рд░ рдкреИрддрд╛рд▓рд╛рдорд╛ рдирдЪрд┐рд▓рд╛рдЙрдиреЗ рд░рд╛рддрд╛ рдбрд╛рдмрд░рд╣рд░реВ рдЖрдЙрди рд╕рдХреНрдЫрдиреНред рдпрд╕рд╕рдБрдЧреИ рдЬреНрд╡рд░реЛ рдЖрдЙрдиреЗ, рдЧреНрд░рдиреНрдереА рд╕реБрдиреНрдирд┐рдиреЗ рд░ рдХрдкрд╛рд▓ рдЭрд░реНрдиреЗ рдЬрд╕реНрддрд╛ рд▓рдХреНрд╖рдг рджреЗрдЦрд┐рдиреНрдЫрдиреНред
Palm/Sole Rash
Distinctive reddish-brown spots.
Mucous Patches
Sores in the mouth or genital area.
The Latent (Hidden) Stage
If untreated, syphilis enters a 'hidden' stage where there are no visible symptoms. This can last for 10-20 years. You are still infected, and the bacteria can be detected via a VDRL blood test.
[рдиреЗрдкрд╛рд▓реА] рдЙрдкрдЪрд╛рд░ рдирдЧрд░реЗрдорд╛ рд╕рд┐рдлрд┐рд▓рд┐рд╕ 'рд▓реБрдХреЗрдХреЛ' рдЕрд╡рд╕реНрдерд╛рдорд╛ рдкреБрдЧреНрдЫред рдпрд╕рдорд╛ рдХреБрдиреИ рдмрд╛рд╣рд┐рд░реА рд▓рдХреНрд╖рдг рджреЗрдЦрд┐рдБрджреИрди рддрд░ рд░рдЧрдд рдЬрд╛рдБрдЪ (VDRL) рдЧрд░реНрджрд╛ рдкреЛрдЬрд┐рдЯрд┐рдн рджреЗрдЦрд┐рдиреНрдЫред рдпреЛ рдЕрд╡рд╕реНрдерд╛ рд╡рд░реНрд╖реМрдВрд╕рдореНрдо рд░рд╣рди рд╕рдХреНрдЫред
Tertiary Syphilis
This is the final, destructive stage. It can lead to Neurosyphilis (brain damage), cardiovascular issues (heart damage), and 'Gummas' (soft tissue tumors). At this stage, while the infection can be killed, the physical damage to the organs is often permanent.
[рдиреЗрдкрд╛рд▓реА] рдпреЛ рдЕрдиреНрддрд┐рдо рд░ рдЦрддрд░рдирд╛рдХ рдЕрд╡рд╕реНрдерд╛ рд╣реЛред рдпрд╕рд▓реЗ рджрд┐рдорд╛рдЧ, рдореБрдЯреБ рд░ рдирд╕рд╛рдорд╛ рд╕реНрдерд╛рдпреА рдХреНрд╖рддрд┐ рдкреБрд░реНтАНрдпрд╛рдЙрдБрдЫред рдпреЛ рдЕрд╡рд╕реНрдерд╛ рдЬреНрдпрд╛рди рд▓рд┐рдиреЗ рдЦрд╛рд▓рдХреЛ рд╣реБрди рд╕рдХреНрдЫред
Congenital Syphilis
A mother can pass syphilis to her unborn child. In Nepal, we strongly recommend syphilis screening for all pregnant women during their first prenatal visit. Early treatment for the mother is highly effective at protecting the baby.
[рдиреЗрдкрд╛рд▓реА] рдЧрд░реНрднрд╡рддреА рдорд╣рд┐рд▓рд╛рдмрд╛рдЯ рдмрдЪреНрдЪрд╛рдорд╛ рд╕рд┐рдлрд┐рд▓рд┐рд╕ рд╕рд░реНрди рд╕рдХреНрдЫред рддреНрдпрд╕реИрд▓реЗ рдиреЗрдкрд╛рд▓рдорд╛ рд╕рдмреИ рдЧрд░реНрднрд╡рддреА рдорд╣рд┐рд▓рд╛рд▓реЗ рдкрд╣рд┐рд▓реЛ рдкрдЯрдХ рдЬрдЪрд╛рдЙрдБрджрд╛ рдиреИ рд╕рд┐рдлрд┐рд▓рд┐рд╕рдХреЛ рдЬрд╛рдБрдЪ рдЧрд░рд╛рдЙрдиреБ рдЕрдирд┐рд╡рд╛рд░реНрдп рдорд╛рдирд┐рдиреНрдЫред
Testing & Costs in Kathmandu
We follow a standard two-step diagnostic protocol for maximum accuracy:
VDRL / RPR (Screening)
Fast and affordable blood test to check for antibodies.
Price: ~Rs. 600
TPHA (Confirmatory)
Highly specific test used to confirm a positive VDRL result.
Price: ~Rs. 1,800
Standard clinical pathway for Syphilis diagnosis in Nepal
Treatment & Cure
The primary treatment for all stages of syphilis is Penicillin GтАФan antibiotic that kills the bacteria. For early stages, a single injection is often sufficient. For late or latent stages, a course of weekly injections is required. We follow the latest WHO and Nepal National Guidelines for dosage and administration.
[рдиреЗрдкрд╛рд▓реА] рд╕рд┐рдлрд┐рд▓рд┐рд╕рдХреЛ рдореБрдЦреНрдп рдЙрдкрдЪрд╛рд░ рдкреЗрдирд┐рд╕рд┐рд▓рд┐рди (Penicillin) рдЗрдиреНрдЬреЗрдХреНрд╕рди рд╣реЛред рд╕реБрд░реБрд╡рд╛рддреА рдЕрд╡рд╕реНрдерд╛рдорд╛ рдПрдЙрдЯреИ рдЗрдиреНрдЬреЗрдХреНрд╕рдирд▓реЗ рдХрд╛рдо рдЧрд░реНрдЫ рднрдиреЗ рдврд┐рд▓реЛ рднрдПрдХреЛ рдЦрдгреНрдбрдорд╛ рд╣рдкреНрддрд╛рдХреЛ рдПрдХрдкрдЯрдХ рдЧрд░реА рдХреЗрд╣реА рд╣рдкреНрддрд╛рд╕рдореНрдо рд▓рдЧрд╛рдЙрдиреБрдкрд░реНрдиреЗ рд╣реБрди рд╕рдХреНрдЫред
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Frequently Asked Questions
Common questions about syphilis symptoms, testing, and treatment in Nepal
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Last Updated: January 14, 2026 |Clinic: STD Treatment Clinic |License: 15834